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Systematic reviews of animal experiments demonstrate poor contributions toward human healthcare

New study published in Reviews on Recent Clinical Trials 2008; 3(2): 89-96

In 20 published systematic reviews, animal models demonstrated significant potential to contribute toward the development of clinical interventions in only two cases, one of which was contentious. Seven additional reviews failed to demonstrate utility in reliably predicting human toxicological outcomes such as carcinogenicity and teratogenicity. Results in animal models were frequently equivocal, or inconsistent with human outcomes. Consequently, animal data may not generally be considered useful for these purposes.

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