These consider some of the issues relating to the use of animals in biomedical research:
Many factors perpetuate animal research, the most obvious of which is tradition. The animal research paradigm is very deeply embedded within research institutions. Laboratories, researchers’ careers, technologies, publication practices and funding streams are now ‘locked-in’ to the paradigm. For example, it is easier and faster to publish papers based on animal research than on human research, and a good publication record will attract funding to continue that research.
Pharmaceutical companies continue to do animal tests because regulators require them to do so and because (despite their lack of reliability) animal tests provide liability protection in court when drugs injure or kill people. Yet most of the animal tests accepted by regulators have never been validated.
By Rebecca Ram This month marks World Liver Day (held every year on 19 Apr) to raise awareness about diseases of the second largest organ in the body. After the brain, the liver is the most complex organ and is vital to the efficient control of the gastrointestinal (digestive) system. Liver diseases account for approximately […]New Approach Methodologies in COVID-19: systematic review into the neurological effects of SARS-CoV-2 infection presented at SOT (Society of Toxicology) Congress 2022
By Rebecca Ram Launched nearly two years ago, the CIAO project (Modelling the Pathogenesis of COVID-19 using the Adverse Outcome Pathway Framework) involves the collaboration of scientific experts to identify the chemical and biological events involved in the body’s response to the SARS-CoV-2 virus. Expert working groups are established across a number of areas, for […]